Monday, 29 June 2015

Depression in Men: Causes, Symptoms and Treatment


According to the World Health Organization, Depression is a global epidemic and nearly 5% of the world’s population suffers from this condition. In North America, 9% of the population is said to suffer from depression, of which nearly 6 million are men. Although women are more prone to depression than men, men are four times more likely to commit suicide from depression, than women.

(Sources: EverydayHealth, CDC, NIMH and Healthline)
 
Unlike women who freely admit feelings of depression and seek treatment, men are less forthcoming. The primary reason for their inhibition is because of cultural stereotypes that expect men to be ‘strong’ or ‘in control’ of their emotions. As a result, men suffering from depression tend to discuss physical symptoms and mask the real reason for their problems. Consequently why, depression in men is not easily recognizable.

Other reasons are related to the way men cope with depression. Unlike women, men are more likely to camouflage their feelings of sadness with anger, irritability and aggression. While some men turn to alcohol or drugs to overcome the feeling of isolation, others may spend more hours at work. There is a stigma attached to mental illness of any kind, including depression, and admitting it can have an impact on the man’s career.

Undergoing treatment is again an issue, as taking time away from work can disrupt the man’s career, and in families where the man is the sole breadwinner, this can severely impact the financial health of the family. Further, depression and the treatment for depression causes sexual dysfunction in most men,thereby creating a vicious circle of despair. That is the reason men are more likely to use strong means of ending their lives (such as shooting or hanging themselves) unlike women who attempt suicide using soft methods.

Causes

Constant ongoing research and findings reveal that depression is not related to an individual’s moods or way of thinking, but is a serious condition that results from changes in the patient’s brain chemistry. However, despite extensive research, there is no clarity on the root cause of these changes. It has been found that neurotransmitters, or chemicals used by the nerves to communicate with each other, do not function properly at times. As a result, some areas of the brain are inactive while others are active causing an imbalance in the patient’s moods, thoughts, feelings and behavior.

Triggers and Risk Factors 
  • Loneliness and lack of support system, such as friends and family
  • Inability to handle stress at work, school or at home
  • A history of substance abuse
  • Marital, financial and career issues
  • Trauma or abuse in childhood
  • Disease and disability in old age
  • Death of a friend or family member
  • Chronic ailments such as Cancer, Diabetes, Heart disease, HIV and Stroke

Symptoms of Male Depression
  • Fatigue, lack of energy and enthusiasm in routine activities
  • Lack of interest in leisure or fun activities
  • Inability to concentrate
  • Suicidal thoughts
  • Physical pain and discomfort, including headache, backache, indigestion, insomnia, and sexual dysfunction
  • Angry, violent and abusive behavior
  • Reckless behavior such as rash driving, playing dangerous sports, and unsafe sex

Forms of Depression
  • Major depression: Lasts for weeks to a few months. Typical symptoms include inability to work, irregular eating, poor sleep, and lack of interest in any activity
  • Psychotic depression:Lasts for weeks to a few months. Typical symptoms include inability to differentiate reality from imagination. Patients experience excessive guilt, despair, a feeling of worthlessness, imagined voices, and suicidal thoughts
  • Persistent depressive disorder:Lasts for months to couple of years at a stretch. Typical symptoms include being permanently depressed along with some of the symptoms of major depression (dysthymia) and chronic major depression

Treatment 
  • Drugs: Antidepressants, which manipulate specific chemicals in the brain, are used to treat depression. These are of two types: SSRIs (selective serotonin reuptake inhibitors) and SNRIs (serotoninnorepinephrine reuptake inhibitors)
  • Counseling or Talk Therapy: is found to be effective in treating mild forms of depression that last for several months
  • Psychotherapy: Different forms of psychotherapy such as psychoanalysis, cognitive therapy, behavioral therapy, psychodynamic therapy, interpersonal therapy, experiential therapy and Insight-oriented therapy are employed to treat depression
  • Lifestyle changes which include regular exercise, nutritious diet, adequate sleep and counseling for better stress management

Depression can be treated effectively when diagnosed in time. If you suffer from any of the symptoms mentioned here, contact your primary care physician. He/she will conduct a thorough examination and recommend you to a specialist who will plan the right course of treatment for you.

Wednesday, 17 June 2015

Detection and Treatment of Lung Cancer

Lung Cancer is the most prevalent form of cancer in the US currently, and causes more deaths than other chronic types of cancer such as prostrate, colorectal and breast cancer combined 

  • In 1987, deaths due to lung cancer in women exceeded the number of deaths due to breast cancer
  • The estimated number of deaths from lung cancer this year, are nearly 160,000
  • Survival rate of people diagnosed with lung cancer is the lowest compared to other forms of cancer. Over 50% of people diagnosed with lung cancer die within a year of diagnosis
(Sources: www.cdc.gov and www.lung.org)

Risk Factors
  • Smoking - is the primary cause of lung cancer. Even if you have quit smoking recently, you could still be at risk through years of smoking, and must be screened for lung cancer
  • Second-hand smoke -If you live with a spouse, sibling, partner or roommate who smokes, you are at as much risk as the smoker
  • Exposure to Radiation–this is a natural element that is produced by the breakdown of uranium,and itemanates significant levels of radiation. Radon accumulates in buildings, soil, air and water, which can put the resident at risk
  • Exposure to harmful chemicals -toxic chemicals like asbestos, arsenic and chromium can be carcinogenic with prolonged exposure. If you work in a production plant and handle these chemicals routinely, you are at high risk of developing lung cancer
  • Heredity - If you have a family history of lung cancer, you are at risk even if you are not a smoker or exposed to toxic substances, constantly

Symptoms

Compared to other types of cancer which exhibit symptoms, lung cancer does not present typical symptoms till an advanced stage (late Stage II and early Stage III). Common symptoms include:
  • Persistent cough that doesn't cease with time
  • Rasping and prolonged bouts of cough typical of smokers, called "smoker's cough"
  • Traces of blood in the sputum
  • Fluid in the chest, or ‘Pleural effusion’
  • Shortness of breath caused by pleural effusion
  • Chest pain, wheezing and hoarse voice
  • Weight loss
  • Pain in the bones and headache, which can be due to the cancer metastasizing to other parts of the body, like the bones and brain

Diagnosis
  • Regular screening: If you are over 55 years of age, smoke regularly or have quit smoking in the recent past, you are required to take a CT scan of your lungs once a year. The CT scan may show small lesions (tissue that looks abnormal) which could be cancerous
  • Sputum cytology:You will be asked to cough and produce sputum which is then examined under a microscope for lung cancer cells
  • Biopsy: Tissue samples from your lung(s), lymph nodes and liver are collected using endoscopic methods and examined for lung cancer cells
 
Treatment
  • Staging – this is the first step in the treatment process, wherein the Oncologist (cancer specialist) will analyze the stage of lung cancer (stage I, II, III or IV)
  • Surgery -this is preferred, as the surgeon can remove the cancerous tissue completely
  • Radiation -when the cancerous tissue is inaccessible, high-energy X-rays are used to burn out the cancerous tissue
  • Chemotherapy -this is generally administratedafter surgery and radiation, to destroy any remnants of cancerous tissue
  • Drugs - New-age drugs that target specific behaviors in cancerous cells, such as Bevacizumab, Erlotinib and Crizotinib are used to disable and destroy the cancerous tissue
If you are a smoker, handle hazardous chemicals, or have a family history of lung cancer, contact your primary care physician, who will conduct the requisite tests and recommend a comprehensive course of treatment.